Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127239 | 0.83 | ALDH1A1 (0.48) | MAPK1TRPV4IDO1DNMT1DNMT3L | |
| SCHEMBL6949091 | 0.78 | PTGES2 (0.57) | AHRTRPV4PTGES2HSD11B1 | |
| SCHEMBL8765653 | 0.73 | PTPRC (0.46) | TRPV4PTGES2IDO1DNMT1DNMT3L | |
| SCHEMBL2229496 | 0.73 | MCOLN3 (0.34) | TRPV4PTGES2IDO1DNMT1DNMT3L | |
| SCHEMBL6294222 | 0.72 | CA1 (0.48) | MAPK1IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL5679063 | 0.72 | CA12 (0.43) | IDO1ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL6291104 | 0.72 | ALDH1A1 (0.43) | TRPV4ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4458304 | 0.72 | AHR (0.63) | AHRMAPK1IDO1ALDH1A1HSD17B10 | |
| SCHEMBL16067 | 0.72 | HSD11B1 (0.47) | TRPV4ALDH1A1HSD17B10TDP1HSD11B1 | |
| SCHEMBL29805295 | 0.72 | AHR (0.63) | AHRMAPK1IDO1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |