SCHEMBL2229520

SCHEMBL2229520

NSc1nc2c3c(ccc2s1)CCOCC3

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5205910 0.86
SCHEMBL12482357 0.78 DYRK1A (0.42)
SCHEMBL4193415 0.75 CA2 (0.40) KDM4EPKM
SCHEMBL9422415 0.68 KDM4E (0.40) KDM4EALDH1A1PKMHPGDALOX15
SCHEMBL8089188 0.68 MAPT (0.41) KDM4EALDH1A1PKMHPGDALOX15
SCHEMBL1706586 0.67 SMN1; SMN2 (0.48) KDM4EALDH1A1PKMHPGDALOX15
SCHEMBL8088211 0.65 ALDH1A1 (0.53) KDM4EALDH1A1PKMHPGDALOX15
SCHEMBL20362099 0.63 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HSD17B10
SCHEMBL4443518 0.62 ALDH1A1 (0.31) ALDH1A1
SCHEMBL2046979 0.61 PSMD14 (0.36) KDM4EALDH1A1PKMHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024015956-A1 RUBBER COMPOSITIONS CONTAINING PHLOROGLUCINOLIC RESINS FOR USE IN TIRE TREADS OF HEAVY VEHICLES SUMITOMO CHEMICAL ADVANCED TECHNOLOGIES, LLC, D.B.A. SUMIKA ELECTRONIC MATERIALS (US) 2024-01-18 WO disclosed
EP-4182387-A1 REINFORCED ELASTOMER COMPOSITION Omya International AG (CH) 2023-05-24 EP disclosed
WO-2023046645-A2 ETHYLENE-A-OLEFIN-NON-CONJUGATED DIENE COPOLYMERS AND BLENDS THEREOF WITH A HIGH DIENE CONTENT PER POLYMER CHAIN ARLANXEO NETHERLANDS B.V. (NL) 2023-03-30 WO disclosed
EP-4149985-A1 ETHYLENE-COPOLYMER RUBBERS Arlanxeo Netherlands B.V. (NL) 2023-03-22 EP disclosed
WO-2022013333-A1 REINFORCED ELASTOMER COMPOSITION OMYA INTERNATIONAL AG (CH) 2022-01-20 WO disclosed
WO-2021228951-A1 ETHYLENE-COPOLYMER RUBBERS ARLANXEO NETHERLANDS B.V. (NL) 2021-11-18 WO disclosed
EP-3856793-A1 CARBON BLACK FOR IMPROVED AUTOMOTIVE ANTI-VIBRATION RUBBER COMPOUND PERFORMANCE Birla Carbon U.S.A., Inc. (US) 2021-08-04 EP disclosed
EP-3697247-A1 OUTSOLE ANS METHOD FOR MAKING THE SAME NIKE Innovate C.V. (US) 2020-08-26 EP disclosed
EP-3645281-A1 COMPOSITE MATERIALS, METHODS OF MAKING, METHODS OF USE, AND ARTICLES INCORPORATING THE COMPOSITE MATERIALS NIKE Innovate C.V. (US) 2020-05-06 EP disclosed
WO-2020069098-A1 CARBON BLACK FOR IMPROVED AUTOMOTIVE ANTI-VIBRATION RUBBER COMPOUND PERFORMANCE BIRLA CARBON U.S.A., INC. (US) 2020-04-02 WO disclosed
EP-0497379-B1 Organic polymer solution NITTO DENKO CORP (JP) 2000-08-02 EP disclosed
EP-0897675-A1 ENERGY CONVERSION COMPOSITION Shishiai-Kabushikigaisha (JP) 1999-02-24 EP disclosed
EP-0643703-A1 2-PYRAZINE DERIVATIVES AND THEIR USE IN RUBBER MONSANTO COMPANY (US) 1995-03-22 EP disclosed
WO-1993025537-A1 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER MONSANTO COMPANY (US) 1993-12-23 WO disclosed
WO-1993025541-A1 2-PYRAZINE DERIVATIVES AND THEIR USE IN RUBBER MONSANTO COMPANY (US) 1993-12-23 WO disclosed
US-5205965-A Solvent containing dissolved polyaniline, protonic acid, oxidizing agent, oxidation catalyst; casting electrically conductive film NITTO DENKO CORPORATION (JP) 1993-04-27 US disclosed
EP-0497379-A1 Organic polymer solution NITTO DENKO CORPORATION (JP) 1992-08-05 EP disclosed
EP-0242432-A1 Tire tread rubber composition The B.F. GOODRICH Company (US) 1987-10-28 EP disclosed
US-4512962-A Hormite inclusion complex with adsorbed sulphur or sulphur donor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-04-23 US disclosed
US-3953270-A EXTRUSION, FREEZING, WRAPPING WITH TEXTILE YARNS GENERAL MOTORS CORPORATION (US) 1976-04-27 US disclosed