Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300359 | 0.84 | L3MBTL1 (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23685295 | 0.81 | CTSC (0.34) | L3MBTL1NOD1POLBKMT2A | |
| SCHEMBL15088198 | 0.81 | BMP1 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25454303 | 0.80 | ALDH1A1 (0.42) | FOLH1 | |
| SCHEMBL25603577 | 0.80 | L3MBTL1 (0.35) | L3MBTL1NOD1POLBKMT2AFOLH1 | |
| SCHEMBL23446431 | 0.79 | ALDH1A1 (0.36) | KISS1R | |
| SCHEMBL23446266 | 0.79 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL12249240 | 0.78 | KISS1R (0.32) | FOLH1KISS1R | |
| SCHEMBL23446779 | 0.77 | L3MBTL1 (0.32) | L3MBTL1NOD1POLBKMT2AFOLH1 | |
| SCHEMBL20099412 | 0.76 | NOD1 (0.34) | NOD1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021109351-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2020155497-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2020-08-06 | — | — | WO | disclosed |