Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 7/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520648 | 0.90 | HRH3 (0.44) | GNAO1GNAI3GNAI1HRH3 | |
| SCHEMBL13061302 | 0.85 | GNAO1 (0.42) | GNAO1GNAI3GNAI1HRH3ACHE | |
| SCHEMBL17424060 | 0.84 | GNAO1 (0.59) | GNAO1GNAI3GNAI1HRH3KCNH2 | |
| SCHEMBL14380398 | 0.84 | GNAO1 (0.59) | GNAO1GNAI3GNAI1HRH3KCNH2 | |
| SCHEMBL24754307 | 0.82 | NCF1 (0.45) | GNAO1GNAI3GNAI1HRH3ACHE | |
| Fluoride SCHEMBL30212677 | 0.82 | GNAO1 (0.57) | GNAO1GNAI3GNAI1HRH3KCNH2 | |
| SCHEMBL7908231 | 0.82 | CYP1A2 (0.46) | GNAO1HRH3 | |
| SCHEMBL12112146 | 0.82 | CYP1A2 (0.54) | GNAO1GNAI3GNAI1HRH3KCNH2 | |
| SCHEMBL84814 | 0.82 | GNAI3 (0.52) | GNAO1GNAI3GNAI1DRD2DRD3 | |
| SCHEMBL6663038 | 0.82 | GNAI3 (0.52) | GNAO1GNAI3GNAI1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160193-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |