SCHEMBL84814

SCHEMBL84814

CCCCN1CCN(CC)CC1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 3/20 0.52
GNAO1 P09471 3/20 0.52
GNAI1 P63096 3/20 0.52
SIGMAR1 Q99720 1/20 0.43
GLB1 P16278 1/20 0.43
DRD2 P14416 2/20 0.42
DRD3 P35462 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663038 1.00 GNAI3 (0.52) GNAI3GNAO1GNAI1SIGMAR1GLB1
SCHEMBL6529493 0.92 GNAI3 (0.61) GNAI3GNAO1GNAI1SIGMAR1
SCHEMBL18538874 0.91 GNAI3 (0.58) GNAI3GNAO1GNAI1SIGMAR1GLB1
SCHEMBL1537447 0.91
SCHEMBL2318272 0.91 GNAI3 (0.58) GNAI3GNAO1GNAI1SIGMAR1GLB1
SCHEMBL1043894 0.91 GNAI3 (0.58) GNAI3GNAO1GNAI1SIGMAR1GLB1
SCHEMBL11737731 0.90 GNAO1 (0.65) GNAI3GNAO1GNAI1SIGMAR1
SCHEMBL11733529 0.90 GNAO1 (0.65) GNAI3GNAO1GNAI1SIGMAR1
SCHEMBL11736163 0.90 GNAO1 (0.65) GNAI3GNAO1GNAI1SIGMAR1
SCHEMBL10254568 0.90 GNAO1 (0.65) GNAI3GNAO1GNAI1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105449276-B A kind of piperazine ionic liquid lithium-ion battery electrolytes 中南大学 2018-07-17 CN claimed
CN-105449276-A Piperazine ionic liquid electrolyte of lithium ion battery UNIV CENTRAL SOUTH 2016-03-30 CN claimed
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed
WO-2023242598-A1 BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LIMITED (GB) 2023-12-21 WO disclosed
US-20230312498-A1 NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS UNIVERSITY OF MARYLAND, BALTIMORE 2023-10-05 US disclosed
US-11730720-B2 ALK5 inhibitors THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-08-22 US disclosed
US-11718595-B2 Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-08-08 US disclosed
WO-2023092242-A1 MULTI-MOTIF DENDRONS AND THEIR SUPRAMOLECULAR STRUCTURES AND USES THEREOF THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2023-06-01 WO disclosed
WO-2023083194-A1 WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF 杭州格博生物医药有限公司 2023-05-19 WO disclosed
WO-2023019181-A1 SARS-COV-2 LIPID NANOPARTICLE VACCINE FORMULATIONS MODERNATX, INC. (US) 2023-02-16 WO disclosed
WO-2023003862-A1 CXCR4 MODULATORS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2023-01-26 WO disclosed
US-20090312319-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS INTELLIKINE 2009-12-17 US disclosed
US-7612064-B2 Sulfopyrroles TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-03 US disclosed
US-20090036429-A1 Hydroxypiperidine Derivatives and Uses Thereof AVALON PHARMACEUTICALS 2009-02-05 US disclosed
US-7384952-B2 Pyrazolopyrimidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-06-10 US disclosed
US-7384952-B2 Pyrazolopyrimidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-06-10 US disclosed
EP-1857459-A2 Pyrazolopyrimidine compound and a process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 2007-11-21 EP disclosed
US-20070232604-A1 receptor kinase inhibitors such as 3-(2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenyl}-benzo[d]imidazo[2,1-b]thiazol-7-yl)-N-(2-morpholin-4-yl-ethyl)-propionamide; flk inhibitors AMBIT BIOSCIENCES CORPORATION 2007-10-04 US disclosed
US-20070060570-A1 Sulfopyrroles TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-03-15 US disclosed
US-4992150-A Telomer with alpha-olefin;oil and fuel additive NIPPON OIL CO, LTD. (JP) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312319-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS PIK3CA, PIK3CG, PIK3CB GNAI3 272/4885GNAO1 718/4885GNAI1 288/4885
US-20070060570-A1 Sulfopyrroles TYK2, ARSA, SULT2A1 GNAI3 1361/4885GNAO1 2171/4885GNAI1 1366/4885
US-20230312498-A1 NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS MAPK1, MAPK8, MAPK4 GNAI3 1151/4885GNAO1 1273/4885GNAI1 740/4885
US-11730720-B2 ALK5 inhibitors ALK, ACVR1, ACVRL1 GNAI3 512/4885GNAO1 1270/4885GNAI1 715/4885
US-20070232604-A1 receptor kinase inhibitors such as 3-(2-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-phenyl}-benzo[d]imidazo[2,1-b]thiazol-7-yl)-N-(2-morpholin-4-yl-ethyl)-propionamide; flk inhibitors GRK2, GRK3, BLK GNAI3 674/4885GNAO1 1526/4885GNAI1 816/4885
US-11718595-B2 Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors MAPK1, MAPK8, MAPK4 GNAI3 1151/4885GNAO1 1273/4885GNAI1 740/4885
US-20090036429-A1 Hydroxypiperidine Derivatives and Uses Thereof HPGDS, HPGD, DPYD GNAI3 1849/4885GNAO1 2920/4885GNAI1 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.