SCHEMBL2230284

SCHEMBL2230284

CCCCCCCC(C(=O)O)C(=O)N(NC(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.48
PRSS1 P07477 3/20 0.46
CTSG P08311 3/20 0.46
CTRB1 P17538 3/20 0.46
CMA1 P23946 3/20 0.46
HDAC1 Q13547 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC2 Q92769 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231656 1.00 NAAA (0.48) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL2231486 0.99 NAAA (0.46) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL5685341 0.81 NAAA (0.50) NAAAPRSS1POLBLMNAHSD17B10
Benzoic Acid Hydrazide SCHEMBL1892700 0.77 NAAA (0.56) NAAAPRSS1CTSGCTRB1CMA1
Benzoic Acid Hydrazide SCHEMBL2231658 0.77 NAAA (0.56) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL27794648 0.76 CES2 (0.45) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL28781481 0.76 CES2 (0.45) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL27769853 0.76 CES2 (0.45) NAAAPRSS1CTSGCTRB1CMA1
SCHEMBL165545 0.76 L3MBTL1 (0.48) NAAAPRSS1CTSGCTRB1CMA1
Benzoic Acid Hydrazide SCHEMBL2231489 0.76 NAAA (0.54) NAAAPRSS1CTSGCTRB1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114729189-A Polyphenylene sulfide resin composition for automobile cooling part and automobile cooling part 东丽株式会社 2022-07-08 CN disclosed
CN-114729188-A Polyphenylene sulfide resin composition for automobile cooling part and automobile cooling part 东丽株式会社 2022-07-08 CN disclosed
US-11306204-B2 Polyphenylene sulfide resin composition, method of producing same, and molded article TORAY INDUSTRIES, INC. (JP) 2022-04-19 US disclosed
US-20210179848-A1 POLYPHENYLENE SULFIDE RESIN COMPOSITION, METHOD OF PRODUCING SAME, AND MOLDED ARTICLE TORAY INDUSTRIES, INC. (JP) 2021-06-17 US disclosed
EP-3708612-A1 POLYPHENYLENE SULFIDE RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE Toray Industries, Inc. (JP) 2020-09-16 EP disclosed
US-20110178211-A1 BIODEGRADABLE POLYESTER RESIN COMPOSITION AND MOLDED BODY COMPOSED OF THE SAME UNITIKA LTD. (JP) 2011-07-21 US disclosed
US-20100292381-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY OBTAINED BY MOLDING THE SAME UNITIKA LTD. (JP) 2010-11-18 US disclosed
EP-2251378-A1 BIODEGRADABLE POLYESTER RESIN COMPOSITION AND MOLDED BODY COMPOSED OF THE SAME UNITIKA LTD. (JP) 2010-11-17 EP disclosed