Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304368 | 0.77 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL683906 | 0.73 | ALOX5 (0.57) | MAOAMAOBRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL20865042 | 0.73 | SIGMAR1 (0.42) | MAOAMAOBMEN1KMT2ACYP3A4 | |
| SCHEMBL20865070 | 0.72 | KDM6B (0.46) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL29783448 | 0.72 | KDM6B (0.46) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL20865040 | 0.72 | CYP4F2 (0.48) | MAOBALOX5LMNA | |
| SCHEMBL22738331 | 0.72 | F2RL3 (0.55) | NPC1MAOAMAOBRAB9AMEN1 | |
| SCHEMBL31166963 | 0.71 | ALOX5 (0.50) | MAOAMAOBRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL20865074 | 0.71 | PTGER1 (0.55) | MAOBKMT2ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL20865038 | 0.71 | MAOB (0.46) | NPC1MAOAMAOBRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200246240-A1 | RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE | L'OREAL (FR) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200246240-A1 | RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE | KRT18, RARA, RBP4 | NPC1 1249/4885MAOA 634/4885MAOB 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.