Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304560 | 0.74 | ABCB1 (0.39) | NPSR1MAPTABCB1ALDH1A1THRB | |
| SCHEMBL14301030 | 0.73 | ABCB1 (0.46) | NPSR1MAPTABCB1ALDH1A1THRB | |
| SCHEMBL16174415 | 0.72 | CYP1A2 (0.51) | KDM4ELMNA | |
| SCHEMBL29034995 | 0.69 | ALDH1A1 (0.49) | NPSR1MAPTABCB1ALDH1A1THRB | |
| SCHEMBL11121575 | 0.67 | KMT2A (0.61) | NPSR1MAPTABCB1MEN1KMT2A | |
| SCHEMBL17324119 | 0.65 | AMY1A (0.41) | NPSR1MAPTABCB1ALDH1A1MEN1 | |
| SCHEMBL2149791 | 0.64 | MAPT (0.54) | NPSR1MAPTALDH1A1GPR55MEN1 | |
| Ether SCHEMBL11236284 | 0.64 | ADRB2 (0.56) | NPSR1MEN1KMT2AKDM4EHTT | |
| SCHEMBL10635979 | 0.64 | ALDH1A1 (0.49) | NPSR1MAPTABCB1ALDH1A1MEN1 | |
| SCHEMBL16348227 | 0.64 | ACHE (0.53) | NPSR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917983-B1 | BETA-HYDROXYPHOSPHONATE FUNCTIONALIZED POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-02-01 | — | — | EP | disclosed |
| WO-2020160094-A2 | BETA-HYDROXYPHOSPHONATE FUNCTIONALIZED POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-06 | — | — | WO | disclosed |