Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173242 | 0.88 | PARP1 (0.47) | SMARCA2SMARCA4MAPTHDAC4ALDH1A1 | |
| SCHEMBL22305714 | 0.88 | WNT3A (0.45) | SMARCA2SMARCA4MEN1KMT2AABL1 | |
| SCHEMBL22290647 | 0.88 | PARP1 (0.47) | SMARCA2SMARCA4MAPTHDAC4ALDH1A1 | |
| SCHEMBL22305368 | 0.87 | MAPT (0.49) | SMARCA2SMARCA4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22306588 | 0.87 | SMARCA2 (0.45) | SMARCA2SMARCA4MEN1KMT2AABL1 | |
| SCHEMBL22305951 | 0.86 | MAPT (0.55) | MEN1KMT2ASMN1; SMN2MAPTHDAC1 | |
| SCHEMBL22306345 | 0.86 | ROCK2 (0.47) | SMARCA2SMARCA4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22306414 | 0.85 | WNT3A (0.54) | SMARCA2SMARCA4KMT2AABL1ELOVL1 | |
| SCHEMBL22306586 | 0.85 | SMARCA2 (0.43) | SMARCA2SMARCA4MEN1KMT2AABL1 | |
| SCHEMBL22306596 | 0.85 | ALDH1A1 (0.58) | MEN1KMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |