Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305743 | 0.83 | SMARCA2 (0.55) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22306207 | 0.81 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22306193 | 0.80 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22305951 | 0.80 | MAPT (0.55) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22305368 | 0.80 | MAPT (0.49) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22305784 | 0.79 | RAB9A (0.43) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22305714 | 0.78 | WNT3A (0.45) | MAPTKMT2AMEN1CYP3A4TRPA1 | |
| SCHEMBL22306345 | 0.78 | ROCK2 (0.47) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL22290647 | 0.78 | PARP1 (0.47) | MAPTALDH1A1CYP3A4 | |
| SCHEMBL31173242 | 0.78 | PARP1 (0.47) | MAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |