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Spirodiclofen

Spirodiclofen

SCHEMBL2230730

CCC(C)(C)C(=O)OC1=C(c2ccc(Cl)cc2Cl)C(=O)OC12CCCCC2.Cc1cc(C)c(C2=C(OC(=O)CC(C)(C)C)C3(CCCC3)OC2=O)c(C)c1

nearest known ligand 0.34

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.31
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spirodiclofen SCHEMBL29412293 0.87 THRB (0.36) THRBLMNA
Spirodiclofen SCHEMBL27234 0.87 THRB (0.36) THRBLMNA
SCHEMBL16984848 0.83 THRB (0.38) THRBLMNA
SCHEMBL13299105 0.83 THRB (0.43) THRBLMNA
Spiromesifen SCHEMBL25068 0.82 THRB (0.31) THRBLMNA
SCHEMBL3433027 0.81 THRB (0.35) THRBLMNA
SCHEMBL14011106 0.79 PTGS2 (0.36) THRBLMNA
SCHEMBL12747347 0.78 PTGS2 (0.38) THRBLMNA
SCHEMBL17552424 0.78 ALDH1A1 (0.33) THRBLMNA
Spiromesifen SCHEMBL4338518 0.78 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346331-A2 ACTIVE SUBSTANCE COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES Bayer CropScience AG (DE) 2011-07-27 — — EP disclosed
WO-2010054757-A2 ACTIVE SUBSTANCE COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2010-05-20 — — WO disclosed