Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 4/20 | 0.35 |
| ▸ | TLR4 | O00206 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160734 | 0.80 | MAPT (0.59) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL21160712 | 0.80 | TTR (0.43) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL24089827 | 0.74 | TTR (0.40) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL22313950 | 0.73 | RAB9A (0.47) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL21231323 | 0.68 | LMNA (0.41) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL253529 | 0.68 | PIK3CG (0.56) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL8170906 | 0.66 | TAS1R3 (0.46) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL10222344 | 0.66 | GAA (0.53) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL9304822 | 0.65 | RAB9A (0.41) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL9305682 | 0.65 | RAB9A (0.46) | MAPTKDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | MAPT 3407/4885KDM4E 4770/4885NPSR1 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.