Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294035 | 0.85 | MAPT (0.44) | ALDH1A1KDM4EPOLBATMMAPT | |
| SCHEMBL6966015 | 0.82 | KDM4E (0.44) | ALDH1A1RECQLSMN1; SMN2KDM4EPOLB | |
| SCHEMBL6275740 | 0.82 | L3MBTL1 (0.46) | ALDH1A1RECQLSMN1; SMN2KDM4EPOLB | |
| SCHEMBL1964864 | 0.82 | PTGS2 (0.60) | PTGS2CXCL8 | |
| SCHEMBL3743443 | 0.81 | KDM4E (0.43) | ALDH1A1RECQLSMN1; SMN2KDM4EPOLB | |
| SCHEMBL8569167 | 0.80 | GABRA1 (0.41) | KMT2AATMTSHR | |
| SCHEMBL24260205 | 0.79 | L3MBTL1 (0.46) | ALDH1A1RECQLSMN1; SMN2KDM4EPOLB | |
| SCHEMBL11989069 | 0.79 | KDM4E (0.50) | KMT2AALDH1A1SMN1; SMN2KDM4EPOLB | |
| Ammonia Solution, Strong SCHEMBL28139473 | 0.79 | KDM4E (0.42) | ALDH1A1RECQLSMN1; SMN2KDM4EPOLB | |
| SCHEMBL22275806 | 0.78 | GLS (0.47) | KMT2AALDH1A1ATMHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156357-A1 | COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 博诺康源(北京)药业科技有限公司 | 2020-08-06 | — | — | WO | disclosed |