SCHEMBL22319082

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL496611	0.80	SLC6A2 (0.44)	SLC6A2TAAR1TP53CYP2D6LMNA
	SCHEMBL476127	0.70	PTGS1 (0.48)	SLC6A2TAAR1TP53CALM1CYP3A4
	SCHEMBL6960730	0.70	TP53 (0.48)	SLC6A2TAAR1TP53CALM1CYP3A4
	SCHEMBL28365326	0.70	SLC6A2 (0.50)	SLC6A2TAAR1TP53CYP2D6LMNA
	SCHEMBL41195	0.69	CALM1 (0.50)	TAAR1TP53CALM1TSHRALDH1A1
	SCHEMBL16298659	0.67	TP53 (0.43)	TP53CALM1TSHRALDH1A1TRPA1
	SCHEMBL9075638	0.67	TP53 (0.50)	SLC6A2TAAR1TP53CALM1CYP3A4
	SCHEMBL8575145	0.67	TP53 (0.50)	SLC6A2TAAR1TP53CALM1CYP3A4
	SCHEMBL347187	0.65	SLC6A2 (0.64)	SLC6A2TAAR1TP53CYP2D6LMNA
	SCHEMBL703317	0.65	CALM1 (0.45)	TAAR1TP53CALM1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.