Propylene Glycol

Propylene Glycol

SCHEMBL22320908

CC(O)CO.CCO[Si](OCC)(OCC)OCC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
TSHR P16473 4/20 0.38
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL9630641 1.00 TDP1 (0.53) TDP1TSHRHSD17B10ALDH1A1
Isopropyl Alcohol SCHEMBL28183520 0.86 LMNA (0.38) TDP1TSHRHSD17B10ALDH1A1
Isopropyl Alcohol SCHEMBL28165739 0.86 LMNA (0.38) TDP1TSHRHSD17B10ALDH1A1
Butanol SCHEMBL9187169 0.84 TSHR (0.53) TDP1TSHRHSD17B10ALDH1A1
Alcohol SCHEMBL442255 0.80 ALDH1A1 (0.43) TSHRALDH1A1
SCHEMBL8386335 0.78 USP2 (0.39) TSHRALDH1A1
SCHEMBL2722071 0.78 HSD17B10 (0.33) TSHRHSD17B10
Alcohol SCHEMBL8207886 0.77 ALDH1A1 (0.40) TSHRALDH1A1
Ethylene Glycol SCHEMBL9629466 0.77 ALDH1A1 (0.38) TSHRALDH1A1
Ethylene Glycol SCHEMBL9630159 0.77 ALDH1A1 (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111133619-B Metal-air battery 学校法人神奈川大学 2023-05-05 CN disclosed
US-20200259187-A1 POSITIVE-ELECTRODE CATALYST FOR METAL-AIR BATTERY, AND METAL-AIR BATTERY KANAGAWA UNIVERSITY (JP) 2020-08-13 US disclosed
CN-111133619-A Positive electrode catalyst for metal-air battery and metal-air battery 学校法人神奈川大学 2020-05-08 CN disclosed