SCHEMBL2722071

SCHEMBL2722071

CCO[Si](OCC)(OCC)OCCC(C)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.33
TSHR P16473 1/20 0.33
CSNK2A1 P68400 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10624899 0.81 ALDH1A1 (0.36)
SCHEMBL11658167 0.81 ALDH1A1 (0.36)
SCHEMBL11662261 0.81 ALDH1A1 (0.36)
Isopropyl Alcohol SCHEMBL28165739 0.80 LMNA (0.38) HSD17B10TSHR
Isopropyl Alcohol SCHEMBL28183520 0.80 LMNA (0.38) HSD17B10TSHR
SCHEMBL2722133 0.79 CSNK2A1 (0.35) HSD17B10CSNK2A1
Butanol SCHEMBL9187169 0.78 TSHR (0.53) HSD17B10TSHR
Propylene Glycol SCHEMBL22320908 0.78 TDP1 (0.53) HSD17B10TSHR
Propylene Glycol SCHEMBL9630641 0.78 TDP1 (0.53) HSD17B10TSHR
SCHEMBL9548428 0.74 TSHR (0.35) HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120157575-A1 POLYMER COMPOSITION, RUBBER COMPOSITION, AND TIRE OBTAINED USING SAME BRIDGESTONE CORPORATION (JP) 2012-06-21 US disclosed
EP-2447318-A1 POLYMER COMPOSITION, RUBBER COMPOSITION, AND TIRE OBTAINED USING SAME Bridgestone Corporation (JP) 2012-05-02 EP disclosed