Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846131 | 0.82 | NR1H4 (0.71) | RXRARXRBRXRGNR1H4EPHX2 | |
| SCHEMBL7407541 | 0.80 | RXRA (0.58) | RXRARXRBRXRGNR1H4EPHX2 | |
| SCHEMBL9342729 | 0.80 | ALDH1A1 (0.54) | NR1H4ALDH1A1ALOX15LMNA | |
| SCHEMBL9809882 | 0.78 | RXRA (0.59) | RXRARXRBRXRGNR1H4EPHX2 | |
| SCHEMBL30977669 | 0.78 | FFAR1 (0.59) | RXRARXRBRXRGFFAR1KEAP1 | |
| SCHEMBL861913 | 0.77 | RXRA (0.55) | RXRARXRBRXRGNR1H4EPHX2 | |
| SCHEMBL23583035 | 0.77 | NR1H4 (0.54) | RXRARXRBRXRGNR1H4EPHX2 | |
| SCHEMBL69746 | 0.77 | FFAR1 (0.81) | FFAR1KEAP1LMNAL3MBTL1FFAR4 | |
| SCHEMBL23582760 | 0.76 | RXRA (0.58) | RXRARXRBRXRGNR1H4EPHX2 | |
| SCHEMBL22334786 | 0.75 | ALDH1A1 (0.44) | RXRARXRBALDH1A1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2022-06-14 | — | — | US | disclosed |
| US-20200253837-A1 | Dental Materials Based On Redox Systems With Low-Odour Cumene Hydroperoxide Derivatives | IVOCLAR VIVADENT AG (LI) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | GPX4, GPX1, AOX1 | RXRA 1614/4885RXRB 2137/4885RXRG 2366/4885 |
| US-20200253837-A1 | Dental Materials Based On Redox Systems With Low-Odour Cumene Hydroperoxide Derivatives | GPX4, GPX1, AOX1 | RXRA 1614/4885RXRB 2137/4885RXRG 2366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.