Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.59 |
| ▸ | RXRB | P28702 | 10/20 | 0.59 |
| ▸ | RXRG | P48443 | 10/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13008812 | 0.82 | RXRA (0.77) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL9175386 | 0.80 | ALDH1A1 (0.65) | RXRARXRBRXRGLMNATSHR | |
| SCHEMBL22322397 | 0.78 | RXRA (0.54) | RXRARXRBRXRGLMNAALDH1A1 | |
| SCHEMBL18427891 | 0.78 | LMNA (0.86) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL68027 | 0.78 | LMNA (0.86) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL840854 | 0.76 | NR1H4 (0.70) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL10614908 | 0.76 | ALDH1A1 (0.75) | LMNAALDH1A1ALOX15 | |
| SCHEMBL27940962 | 0.76 | RXRA (0.58) | RXRARXRBRXRGABCC4LMNA | |
| SCHEMBL2272003 | 0.75 | RXRA (0.77) | RXRARXRBRXRGABCC4LMNA | |
| Methane SCHEMBL17237476 | 0.74 | NR1H4 (0.68) | RXRARXRBRXRGABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983777-A | Diisopropylbiphenyl mono- and di-hydroperoxides, process for the preparation thereof, and compounds derived therefrom | EASTMAN KODAK COMPANY (US) | 1991-01-08 | — | — | US | disclosed |