SCHEMBL22323901

SCHEMBL22323901

COC(=O)Nc1ccccc1CC(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 4/20 0.44
HPGD P15428 3/20 0.44
LMNA P02545 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
POLB P06746 1/20 0.42
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 3/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
KMT2A Q03164 1/20 0.41
NLRP3 Q96P20 1/20 0.40
CRHBP P24387 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15223404 0.84 ALDH1A1 (0.50) L3MBTL1ALDH1A1HPGDLMNAPOLB
SCHEMBL24780583 0.84 LMNA (0.46) L3MBTL1ALDH1A1LMNAPOLBTP53
SCHEMBL10489756 0.83 HPGD (0.44) L3MBTL1ALDH1A1HPGDLMNAGABRA1
SCHEMBL11440473 0.83 L3MBTL1 (0.53) L3MBTL1ALDH1A1LMNANOS3NOS1
SCHEMBL7209100 0.83 HPGD (0.46) L3MBTL1ALDH1A1HPGDLMNAALOX15
SCHEMBL1836106 0.82 L3MBTL1 (0.51) L3MBTL1ALDH1A1HPGDLMNAALOX15
SCHEMBL9587541 0.82 ALDH1A1 (0.54) ALDH1A1POLBMAPTTAS1R3TAS1R1
SCHEMBL2462870 0.81 HPGD (0.56) L3MBTL1ALDH1A1HPGDLMNAALOX15
SCHEMBL29960499 0.81 HPGD (0.56) L3MBTL1ALDH1A1HPGDLMNAALOX15
SCHEMBL10121309 0.80 POLB (0.56) L3MBTL1ALDH1A1HPGDLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023152566-A1 AGROCHEMICAL ADJUVANTS CRODA INTERNATIONAL PLC (GB) 2023-08-17 WO disclosed
EP-3920697-A1 INHIBITING INSECTICIDE RESISTANCE AND MAKING SUSCEPTIBLE INSECTS HYPER-SUSCEPTIBLE TO PESTICIDES Board Of Trustees Of Michigan State University (US) 2021-12-15 EP disclosed
WO-2020163811-A1 INHIBITING INSECTICIDE RESISTANCE AND MAKING SUSCEPTIBLE INSECTS HYPER-SUSCEPTIBLE TO PESTICIDES BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2020-08-13 WO disclosed
CN-102948980-B Manufacturing method of silk umbrella HANGZHOU PARADISE UMBRELLA GROUP CO LTD 2014-11-26 CN disclosed
CN-102948980-A Manufacturing method of silk umbrella HANGZHOU PARADISE UMBRELLA GROUP CO LTD 2013-03-06 CN disclosed
CN-1171533-C Epiphylatic composition for environment protecting edible fungus culturing material and its sterilization process 张东平 2004-10-20 CN disclosed
CN-1402987-A Epiphylatic composition for environment protecting edible fungus culturing material and its sterilization process ZHANG DONGPING (CN) 2003-03-19 CN disclosed