Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325923 | 0.85 | TAS2R38 (0.41) | ALDH1A1HPGDRAB9AHTTMAPT | |
| SCHEMBL28294431 | 0.83 | ALDH1A1 (0.59) | POLBCYP2C19ALOX15ALDH1A1HPGD | |
| SCHEMBL6282611 | 0.82 | PTGDR2 (0.47) | POLBCYP2C19ALOX15ALDH1A1HPGD | |
| SCHEMBL422636 | 0.76 | RXFP1 (0.61) | POLBCYP2C19RXFP1ALDH1A1HPGD | |
| SCHEMBL29408737 | 0.76 | RXFP1 (0.61) | POLBCYP2C19RXFP1ALDH1A1HPGD | |
| SCHEMBL2342698 | 0.76 | ADRA2C (0.64) | POLBALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL30327328 | 0.76 | ADRA2C (0.64) | POLBALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7719997 | 0.74 | L3MBTL1 (0.54) | POLBALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL31522017 | 0.74 | TDP1 (0.52) | POLBCYP2C19ALOX15ALDH1A1RAB9A | |
| SCHEMBL6694336 | 0.73 | RXFP1 (0.53) | POLBCYP2C19RXFP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |