Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325859 | 0.85 | POLB (0.47) | ALDH1A1NPSR1EPHX1HTTRAB9A | |
| SCHEMBL22339032 | 0.83 | TAS2R38 (0.42) | TAS2R38ALDH1A1NPSR1EPHX1HTT | |
| SCHEMBL22325986 | 0.82 | TDP1 (0.36) | L3MBTL1ALDH1A1NPSR1HTTRAB9A | |
| SCHEMBL28600570 | 0.76 | L3MBTL1 (0.64) | TAS2R38L3MBTL1ALDH1A1HTTRAB9A | |
| SCHEMBL11854131 | 0.70 | TAS2R38 (0.61) | TAS2R38L3MBTL1ALDH1A1EPHX1HTT | |
| SCHEMBL11166000 | 0.70 | ALDH1A1 (0.45) | TAS2R38L3MBTL1ALDH1A1NPSR1EPHX1 | |
| SCHEMBL11313504 | 0.70 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL201794 | 0.68 | ALDH1A1 (0.67) | TAS2R38L3MBTL1ALDH1A1NPSR1EPHX1 | |
| SCHEMBL13323864 | 0.68 | TAS2R38 (0.60) | TAS2R38ALDH1A1NPSR1EPHX1HTT | |
| SCHEMBL31522017 | 0.68 | TDP1 (0.52) | ALDH1A1NPSR1HTTRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |