Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325829 | 0.81 | RHEB (0.43) | BRPF1KEAP1RHEBPDPK1BRD4 | |
| SCHEMBL22326019 | 0.70 | PIN1 (0.35) | KEAP1RHEBBRD4POLBKDM4E | |
| SCHEMBL22325794 | 0.68 | BRD4 (0.42) | BRPF1BRD4 | |
| SCHEMBL22326064 | 0.67 | BRD4 (0.52) | BRPF1PBRM1BRD4 | |
| SCHEMBL32677627 | 0.66 | BRPF1 (0.51) | BRPF1PBRM1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3790885 | 0.64 | KEAP1 (0.70) | BRPF1KEAP1PDPK1BCHEIKBKB | |
| SCHEMBL30690400 | 0.64 | KEAP1 (0.70) | BRPF1KEAP1PDPK1BCHEIKBKB | |
| SCHEMBL2305754 | 0.64 | BRD4 (0.41) | BRPF1HTR2CBRD4POLB | |
| Acetic Acid SCHEMBL27953390 | 0.61 | KEAP1 (0.56) | KEAP1PDPK1BCHEIKBKBCHUK | |
| SCHEMBL31522091 | 0.61 | NR1H4 (0.38) | DHODHPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |