Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326019 | 0.83 | PIN1 (0.35) | RHEBKEAP1KDM4EMAPTKMT2A | |
| SCHEMBL22325916 | 0.81 | BRPF1 (0.42) | RHEBKEAP1KDM4EPDPK1BRD4 | |
| SCHEMBL2305754 | 0.75 | BRD4 (0.41) | KMT2AAHRPIM3TNFRIPK1 | |
| SCHEMBL4718619 | 0.70 | KEAP1 (0.49) | RHEBKEAP1KMT2ALTA4HTSHR | |
| SCHEMBL15741308 | 0.68 | TNF (0.42) | KEAP1AHRTRPA1PDPK1PIM3 | |
| SCHEMBL15749988 | 0.67 | ALDH1A1 (0.38) | KEAP1KDM4EMAPTKMT2AAHR | |
| SCHEMBL22326024 | 0.66 | MAOB (0.44) | RHEBKDM4EGLAMAPTKMT2A | |
| SCHEMBL11313504 | 0.66 | ALDH1A1 (0.48) | KDM4EGLAMAPTKMT2ALTA4H | |
| SCHEMBL7089361 | 0.66 | GSTP1 (0.46) | KEAP1LTA4HTSHRAHRPDPK1 | |
| SCHEMBL15662861 | 0.65 | TNF (0.59) | KEAP1KMT2ALTA4HAHRPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |