SCHEMBL22326131

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31694457	1.00	ALOX15 (0.44)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19
	SCHEMBL22336948	0.84	ESR1 (0.31)	CYP3A4MAPK1ESR1ESR2TSHR
	SCHEMBL24191002	0.82	ALDH1A1 (0.36)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19
	SCHEMBL30429291	0.82	ALDH1A1 (0.36)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19
	SCHEMBL22326112	0.77	CYP3A4 (0.46)	ALOX15ALDH1A1MAPTCYP3A4MAPK1
	SCHEMBL28647603	0.77	CYP2D6 (0.52)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19
	SCHEMBL278233	0.77	CYP2D6 (0.52)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19
	SCHEMBL20808843	0.77	CYP2D6 (0.52)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19
	SCHEMBL24191006	0.75	GPR35 (0.41)	ALOX15ALDH1A1CYP2C9CYP2C19MAPT
	SCHEMBL30485784	0.75	CYP2D6 (0.50)	ALOX15ALDH1A1CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.