Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.42 |
| ▸ | NPC1 | O15118 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326543 | 0.86 | RAB9A (0.43) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL22326544 | 0.81 | RAB9A (0.43) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL20174721 | 0.80 | ALDH1A1 (0.42) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL20174337 | 0.77 | ALDH1A1 (0.33) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL22326547 | 0.76 | NPSR1 (0.42) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL20174351 | 0.76 | ACACA (0.37) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL20174739 | 0.75 | NTRK1 (0.40) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL20174690 | 0.74 | PDK2 (0.41) | L3MBTL1 | |
| SCHEMBL21298131 | 0.73 | NPC1 (0.53) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL17716721 | 0.73 | CA1 (0.34) | RAB9ANPC1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | RAB9A 2250/4885NPC1 2492/4885ALDH1A1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.