Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | POLD1 | P28340 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26068622 | 0.94 | POLB (0.45) | POLBPOLA1POLD1TK1TYMS | |
| SCHEMBL24970792 | 0.88 | POLB (0.51) | POLBPOLA1POLD1TK1 | |
| SCHEMBL22327007 | 0.87 | FUT5 (0.38) | POLBPOLA1POLD1 | |
| SCHEMBL26068617 | 0.87 | FUT5 (0.38) | POLBPOLA1POLD1 | |
| SCHEMBL22327062 | 0.86 | POLG (0.44) | POLBPOLA1POLD1 | |
| SCHEMBL22327396 | 0.83 | TK1 (0.43) | TK1TYMS | |
| SCHEMBL22327297 | 0.83 | TK1 (0.43) | TK1TYMS | |
| SCHEMBL22327013 | 0.83 | ENTPD1 (0.38) | POLB | |
| SCHEMBL24973058 | 0.82 | TK1 (0.43) | TK1TYMS | |
| SCHEMBL24971603 | 0.82 | TK1 (0.43) | TK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738072-B1 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738072-B1 | Nucleotide analogues | NUDT1, POLN, TYMP | POLB 12/4885POLA1 61/4885POLD1 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.