⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24971624 | 0.87 | ADORA3 (0.33) | — | |
| SCHEMBL22598549 | 0.81 | METTL3 (0.39) | — | |
| SCHEMBL26068422 | 0.81 | METTL3 (0.39) | — | |
| SCHEMBL25754040 | 0.78 | TYMP (0.43) | — | |
| SCHEMBL20810884 | 0.77 | ADK (0.38) | — | |
| SCHEMBL2611648 | 0.77 | ADK (0.38) | — | |
| SCHEMBL2611621 | 0.73 | CA2 (0.36) | — | |
| SCHEMBL22598353 | 0.72 | POLB (0.37) | — | |
| SCHEMBL12047328 | 0.70 | CA2 (0.36) | — | |
| SCHEMBL22327354 | 0.70 | CA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
| US-10738072-B1 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2020-08-11 | — | — | US | disclosed |