Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381434 | 0.87 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9ATRPM8LMNA | |
| SCHEMBL6974510 | 0.85 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9ATRPM8LMNA | |
| SCHEMBL7230861 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNATSHRMAPK1LTB4R2 | |
| SCHEMBL2290221 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1NPC1RAB9ATSHRMAPK1 | |
| SCHEMBL21026913 | 0.81 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ATSHRMAPT | |
| SCHEMBL4831257 | 0.81 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9ATRPM8LMNA | |
| SCHEMBL1276417 | 0.79 | NPC1 (0.48) | ALDH1A1NPC1RAB9ATSHRMAPK1 | |
| Ether SCHEMBL954914 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ATSHRALOX15 | |
| SCHEMBL4234185 | 0.78 | NPC1 (0.47) | ALDH1A1NPC1RAB9AAPPTSHR | |
| SCHEMBL22312249 | 0.78 | KMT2A (0.52) | ALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355104-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | NIKANG THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | US | disclosed |
| EP-3820474-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | Nikang Therapeutics, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-2536277-B1 | 3-AMINOCARBONYL SUBSTITUTED BENZOYLCYCLOHEXANDIONS AND THEIR APPLICATION AS HERBICIDES | BAYER IP GMBH (DE) | 2016-01-20 | — | — | EP | disclosed |
| US-8557741-B2 | 3-aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-15 | — | — | US | disclosed |
| US-20110207605-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355104-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | ADORA2A, ADORA1, ADORA3 | ALDH1A1 944/4885NPC1 3350/4885RAB9A 2668/4885 |
| US-20110207605-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | DDT, CBR3, CBR1 | ALDH1A1 133/4885NPC1 4861/4885RAB9A 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.