Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4234185 | 0.84 | NPC1 (0.47) | SMN1; SMN2ALDH1A1TSHRALOX5NPC1 | |
| SCHEMBL22312249 | 0.84 | KMT2A (0.52) | SMN1; SMN2ALDH1A1NPC1GRM5KMT2A | |
| SCHEMBL2233053 | 0.82 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1TSHRNPC1MAPT | |
| SCHEMBL19249675 | 0.82 | NPC1 (0.48) | SMN1; SMN2ALDH1A1TSHRALOX5NPC1 | |
| SCHEMBL1276417 | 0.82 | NPC1 (0.48) | SMN1; SMN2ALDH1A1TSHRALOX5NPC1 | |
| SCHEMBL1957356 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2ALOX5NPC1RAB9AMAPK1 | |
| SCHEMBL26383132 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1ALOX5NPC1RAB9A | |
| SCHEMBL10381434 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRALOX5NPC1MAPT | |
| SCHEMBL23656112 | 0.79 | OPRM1 (0.46) | SMN1; SMN2ALDH1A1TSHRALOX5NPC1 | |
| SCHEMBL712779 | 0.79 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1TSHRNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994218-B2 | Simple pantoic acid ester neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use | XENOPORT, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090082440-A1 | SIMPLE PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. | 2009-03-26 | — | — | US | disclosed |
| EP-0236355-A1 | BONE-SEEKING COMPLEXES OF TECHNETIUM-99m | AMERSHAM INTERNATIONAL plc (GB) | 1987-09-16 | — | — | EP | disclosed |
| WO-1987001289-A1 | BONE-SEEKING COMPLEXES OF TECHNETIUM-99m | AMERSHAM INTERNATIONAL PLC (GB) | 1987-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082440-A1 | SIMPLE PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | ADSL, SLC19A1, SLC25A21 | SMN1; SMN2 373/4885ALDH1A1 1362/4885TSHR 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.