SCHEMBL2233208

SCHEMBL2233208

Cc1ccccc1S(=O)(=O)Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.42
EDNRA P25101 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
EDNRB P24530 1/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD11B1 P28845 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6113254 0.81 KMT2A (0.45) TSHRACHEEDNRAKMT2AALDH1A1
SCHEMBL8779786 0.81 CA1 (0.48) TSHRKMT2AALDH1A1TDP1CA1
SCHEMBL4533183 0.79 TSHR (0.47) TSHRACHERAPGEF4EDNRAKMT2A
SCHEMBL29468592 0.79 ALDH1A1 (0.55) TSHRACHERAPGEF4KMT2ALMNA
SCHEMBL475089 0.79 ALDH1A1 (0.55) TSHRACHERAPGEF4KMT2ALMNA
O-Xylene SCHEMBL27858877 0.78 TSHR (0.62) TSHRACHELMNAALDH1A1TDP1
SCHEMBL79052 0.77 TSHR (0.45) TSHRACHERAPGEF4EDNRAKMT2A
SCHEMBL12307 0.77 L3MBTL1 (0.50) TSHRACHERAPGEF4EDNRAALDH1A1
SCHEMBL28278788 0.77 L3MBTL1 (0.50) TSHRACHERAPGEF4EDNRAALDH1A1
SCHEMBL10443671 0.76 KMT2A (0.46) TSHRACHERAPGEF4EDNRAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094637-A1 PROCESS FOR THE PREPARATION OF CYCLIC KETONES ARXADA AG (CH) 2024-05-10 WO claimed
CN-110121491-A 3,4,5- trimethoxy cinnamic acid ester derivant, preparation method and the skin lightening compositions containing the derivative 株式会社爱茉莉太平洋 2019-08-13 CN claimed
CN-106397277-A Synthesis method of selective methylating agent methyl p-toluenesulfonate 厦门莱恩斯特信息科技有限公司 2017-02-15 CN claimed
WO-2017009866-A1 NOVEL RECOVERY AND RECYCLING PROCESS OF RACEMIC 4-(4-DIMETHYLAMINO)-1-(4'-FLUOROPHENYL)-1-(HYDROXYBUTYL)-3-(HYDROXYMETHYL)-BENZONITRILE IPCA LABORATORIES LIMITED (IN) 2017-01-19 WO claimed
CN-105566172-A Synthetic method of selective methylation reagent methyl p-toluenesulfonate CHENGDU DONGDIAN AIER SCIENCE AND TECH CO LTD 2016-05-11 CN claimed
CN-102010352-A Method for synthesizing N-sulfimide by using ammonia water as nitrogen source UNIV SOUTH CHINA TECH 2011-04-13 CN claimed
CN-101801429-A The immobilization on medical treatment device of dyestuff and antimicrobial BAXTER INT 2010-08-11 CN claimed
EP-1169364-B1 NOVEL ABA TRIBLOCK AND DIBLOCK COPOLYMERS AND METHODS OF PREPARING THE SAME CALIFORNIA INST OF TECHN (US) 2009-07-29 EP claimed
US-6974876-B2 Method for preparing intermediates useful in synthesis of retroviral protease inhibitors G.D. SEARLE & CO. (US) 2005-12-13 US claimed
CN-1203071-C Polysaccharidic esters of N-derivatives of glutamic acid OULANDE PHARMACEUTICAL LTD (IE) 2005-05-25 CN claimed
EP-1169364-A4 NOVEL ABA TRIBLOCK AND DIBLOCK COPOLYMERS AND METHODS OF PREPARING THE SAME CALIFORNIA INST OF TECHN (US) 2003-07-23 EP claimed
CN-1418103-A Polysaccharidic esters of N-derivatives of glutamic acid OULANDE PHARMACEUTICAL LTD (IE) 2003-05-14 CN claimed
US-20030013825-A1 Novel ABA triblock and diblock copolymers and methods of preparing the same CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-01-16 US claimed
WO-2003000739-A1 REGIOSELECTIVELY RETICULATED POLYSACCHARIDES EURAND PHARMACEUTICALS LTD (IE) 2003-01-03 WO claimed
US-6410666-B1 CONTACTING A CYCLOALKENE WITH CHAIN TRANSFER AGENT IN PRESENCE OF METATHESIS CATALYST FORMING TELECHELIC POLYMER; REACTING WITH ALKENE CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-06-25 US claimed
US-6380400-B1 DIMETHYLTHIOCARBAMIC ACID ESTER; VIRICIDES FEDIJ VICTOR (US) 2002-04-30 US claimed
EP-1169364-A1 NOVEL ABA TRIBLOCK AND DIBLOCK COPOLYMERS AND METHODS OF PREPARING THE SAME CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-01-09 EP claimed
CN-1322708-A Preparation of di-tert-butyl dicarbonate YU BAIXING (CN) 2001-11-21 CN claimed
WO-2000055218-A1 NOVEL ABA TRIBLOCK AND DIBLOCK COPOLYMERS AND METHODS OF PREPARING THE SAME CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-09-21 WO claimed
WO-2000015625-A2 METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2000-03-23 WO claimed