Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278788 | 1.00 | L3MBTL1 (0.50) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| Bromide SCHEMBL28167960 | 0.97 | L3MBTL1 (0.48) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| Cyanide SCHEMBL27700014 | 0.93 | L3MBTL1 (0.45) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| Chloroform SCHEMBL28290992 | 0.91 | L3MBTL1 (0.44) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| Carbon Tetrachloride SCHEMBL28292390 | 0.91 | L3MBTL1 (0.44) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| SCHEMBL8106699 | 0.83 | LOX (0.47) | L3MBTL1ALDH1A1KDM4ETP53BCAT2 | |
| SCHEMBL17922579 | 0.81 | HSD11B1 (0.47) | L3MBTL1TSHRACHEALDH1A1KDM4E | |
| SCHEMBL29468592 | 0.81 | ALDH1A1 (0.55) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| SCHEMBL4533183 | 0.81 | TSHR (0.47) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 | |
| SCHEMBL475089 | 0.81 | ALDH1A1 (0.55) | L3MBTL1TSHRACHERAPGEF4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 853 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499063-A | Comprehensive recycling treatment system and method for p-methylsulfonyl toluene wastewater | 利民化学有限责任公司 | 2020-08-07 | — | — | CN | claimed |
| CN-107501141-B | A kind of preparation method of pair of methylsulfonyltoluene | 山东国邦药业有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-110305047-A | A kind of method that continuous flow prepares 2- nitro -4- methylsulfonyltoluene | 海利贵溪化工农药有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110265670-A | A kind of method of Subjective and Objective strategy synthetic nitrogen, the double-doped carbon-based dual purpose catalyst of other hetero atoms | 北京化工大学 | 2019-09-20 | — | — | CN | claimed |
| CN-110256308-A | Synthesis process of mesotrione | 湖北广富林生物制剂有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-110229088-A | Preparation method of mesotrione intermediate | 湖北广富林生物制剂有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-110078646-A | A kind of production method of pair of methylsulfonyltoluene | 浙江嘉化新材料有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-106957250-B | A kind of bromination process of pair of methylsulfonyltoluene | 湖北君尚科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-106883155-B | A kind of synthetic method of pair of methyl sulfone benzaldehyde | 江西天戌药业有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-109503437-A | The preparation method of 2- nitryl-4-thiamphenicol benzoic acid | 江苏新鑫隆医药科技股份有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-102924346-A | Method for synthesizing methyl sulfone base dibromo toluene | SHANDONG RUNKE CHEMICAL CO LTD | 2013-02-13 | — | — | CN | claimed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | claimed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | claimed |
| EP-2200440-A1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | Crestone, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| EP-1718605-B1 | PROCESSES FOR THE PREPARATION OF ARYL-AND HETEROARYL-ALKYLSULFONYL HALIDES | WYETH CORP (US) | 2009-06-17 | — | — | EP | claimed |
| US-20090117406-A1 | CONCENTRATE FOR FILM PRESERVATION | ISP INVESTMENTS INC. | 2009-05-07 | — | — | US | claimed |
| WO-2009015208-A1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | REPLIDYNE, INC. (US) | 2009-01-29 | — | — | WO | claimed |
| EP-0594027-B1 | Method for the preparation of methylsulphonylbenzoic acids | BASF AG (DE) | 1996-08-21 | — | — | EP | claimed |
| US-5424481-A | Preparation of methylsulfonylbenzoic acids | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | claimed |
| US-5300143-A | Water soluble dye, sulfone, and amide or cyclic amine | XEROX CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | L3MBTL1 4619/4885TSHR 2748/4885ACHE 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.