Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL814832 | 0.88 | MAPT (0.44) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL3398525 | 0.88 | HTR1A (0.58) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL19880724 | 0.85 | HTR1A (0.39) | HTR1AKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL25193508 | 0.80 | HTR1A (0.44) | HTR1AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL16372549 | 0.79 | HTR1A (0.48) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL10359370 | 0.79 | KDM4E (0.59) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL12113657 | 0.79 | HTR1A (0.48) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL15783301 | 0.79 | MAPT (0.38) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL25690903 | 0.78 | HTR1A (0.53) | HTR1AKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL817936 | 0.78 | MAPT (0.43) | HTR1AKDM4EALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744916-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LIMITED | 2023-09-05 | — | — | US | disclosed |
| US-20210275674-A1 | RADIOPAQUE POLYMERS | Boston Scientific Medical Device Limited (IE) | 2021-09-09 | — | — | US | disclosed |
| US-20210236660-A1 | IMAGEABLE POLYMERS | BIOCOMPATIBLES UK LTD. | 2021-08-05 | — | — | US | disclosed |
| US-11040104-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LTD. (GB) | 2021-06-22 | — | — | US | disclosed |
| US-10925979-B2 | Imageable polymers | BIOCOMPATIBLES UK LTD. (GB) | 2021-02-23 | — | — | US | disclosed |
| US-20210015963-A1 | RADIOPAQUE POLYMERS | BIOCOMPATIBLES UK LTD. (GB) | 2021-01-21 | — | — | US | disclosed |
| US-20200254099-A1 | RADIOPAQUE POLYMERS | Boston Scientific Medical Device Limited (IE) | 2020-08-13 | — | — | US | disclosed |
| US-20200254117-A1 | IMAGEABLE POLYMERS | Boston Scientific Medical Device Limited (IE) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925979-B2 | Imageable polymers | VHL, FLT4, FLT1 | HTR1A 4509/4885KDM4E 2252/4885ALDH1A1 2674/4885 |
| US-20210275674-A1 | RADIOPAQUE POLYMERS | RXFP3, RXFP1, DAGLA | HTR1A 1327/4885KDM4E 3939/4885ALDH1A1 292/4885 |
| US-20210236660-A1 | IMAGEABLE POLYMERS | VHL, FLT4, FLT1 | HTR1A 4509/4885KDM4E 2252/4885ALDH1A1 2674/4885 |
| US-20200254099-A1 | RADIOPAQUE POLYMERS | RXFP3, RXFP1, DAGLA | HTR1A 1327/4885KDM4E 3939/4885ALDH1A1 292/4885 |
| US-20200254117-A1 | IMAGEABLE POLYMERS | VHL, FLT4, FLT1 | HTR1A 4509/4885KDM4E 2252/4885ALDH1A1 2674/4885 |
| US-11040104-B2 | Radiopaque polymers | RXFP3, RXFP1, DAGLA | HTR1A 1327/4885KDM4E 3939/4885ALDH1A1 292/4885 |
| US-20210015963-A1 | RADIOPAQUE POLYMERS | TPO, PGLS, IQGAP1 | HTR1A 2594/4885KDM4E 1566/4885ALDH1A1 1464/4885 |
| US-11744916-B2 | Radiopaque polymers | TPO, PGLS, IQGAP1 | HTR1A 2594/4885KDM4E 1566/4885ALDH1A1 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.