Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | XBP1 | P17861 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300441 | 0.76 | AKT1 (0.38) | MAPTATMLMNAAKT1ALDH1A1 | |
| SCHEMBL22988641 | 0.73 | KMT2A (0.37) | MAPTXBP1ATMLMNASMN1; SMN2 | |
| SCHEMBL21253891 | 0.70 | AKT1 (0.37) | ATMAKT1ALDH1A1 | |
| SCHEMBL19046658 | 0.70 | AKT1 (0.37) | MAPTPOLBAKT1ALDH1A1L3MBTL1 | |
| SCHEMBL22071486 | 0.69 | CES2 (0.34) | MAPTATMLMNASMN1; SMN2POLB | |
| SCHEMBL23183270 | 0.69 | ATM (0.41) | MAPTATMLMNANPSR1AKT1 | |
| SCHEMBL24975608 | 0.69 | AKT1 (0.33) | ATMAKT1ALDH1A1 | |
| SCHEMBL13808632 | 0.69 | ALDH1A1 (0.34) | MAPTATMLMNASMN1; SMN2NPSR1 | |
| SCHEMBL24884816 | 0.68 | AKT1 (0.35) | MAPTXBP1ATMLMNASMN1; SMN2 | |
| SCHEMBL20625867 | 0.68 | MEN1 (0.32) | ATMLMNAAKT1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |