Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20755618 | 0.84 | MGAM (0.33) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL20744883 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL20744886 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL6980204 | 0.74 | GAA (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL20755930 | 0.73 | HPGD (0.40) | — | |
| SCHEMBL20755811 | 0.72 | HPGD (0.39) | GAATSHR | |
| SCHEMBL1267955 | 0.72 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL22337997 | 0.70 | TSHR (0.39) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2607778 | 0.69 | TET2 (0.38) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL10864918 | 0.69 | TSHR (0.40) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | THE SCRIPPS RESEARCH INSTITUTE | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | BCAT1, AOC3, SPIN3 | MGAM 3257/4885GAA 3962/4885SI 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.