Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22338190 | 0.80 | TSHR (0.41) | TSHRCNR1ALDH1A1GAAKMT2A | |
| SCHEMBL25083274 | 0.78 | TSHR (0.40) | TSHRCNR1ALDH1A1GAAKMT2A | |
| SCHEMBL22338220 | 0.77 | TSHR (0.45) | TSHRALDH1A1GAAKMT2A | |
| SCHEMBL16405258 | 0.74 | GBA1 (0.47) | TSHRCNR1ALDH1A1 | |
| SCHEMBL16407986 | 0.70 | GBA1 (0.43) | TSHRCNR1ALDH1A1 | |
| SCHEMBL21235866 | 0.68 | CNR1 (0.45) | CNR1ALDH1A1GAAKMT2A | |
| SCHEMBL6871210 | 0.68 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL22338143 | 0.67 | KDM4E (0.46) | TSHRALDH1A1GAAKMT2A | |
| SCHEMBL23627012 | 0.65 | DNM1 (0.50) | TSHRALDH1A1KMT2A | |
| SCHEMBL19672577 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |