Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25092811 | 0.75 | KMO (0.33) | EGFR | |
| SCHEMBL23638849 | 0.75 | PPARG (0.33) | — | |
| SCHEMBL16908224 | 0.73 | CYP3A4 (0.35) | LMNAHTTGAA | |
| SCHEMBL22020507 | 0.73 | HSD17B10 (0.37) | MAPK1LMNAHTT | |
| SCHEMBL18059180 | 0.72 | CYP3A4 (0.37) | MAPK1GAA | |
| SCHEMBL19299397 | 0.70 | PTGDR2 (0.39) | MAPK1LMNA | |
| SCHEMBL24773785 | 0.69 | — | — | |
| SCHEMBL19073506 | 0.68 | KDM4E (0.43) | MAPK1LMNAKDM4E | |
| SCHEMBL17625677 | 0.68 | ALDH1A1 (0.46) | MAPK1LMNAKDM4E | |
| SCHEMBL25880803 | 0.68 | LMNA (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163375-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2020-08-13 | — | — | WO | disclosed |