Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.67 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315510 | 0.93 | KDM1A (0.67) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL7758912 | 0.89 | KDM1A (0.64) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL11925397 | 0.89 | KDM1A (0.64) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL9635671 | 0.86 | POLB (0.74) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL7622075 | 0.85 | KDM1A (0.60) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL1870929 | 0.85 | POLB (0.71) | KDM1ARCOR1ALDH1A1LMNAPOLB | |
| SCHEMBL7758133 | 0.84 | KDM1A (0.59) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL9780058 | 0.84 | KDM1A (0.62) | KDM1ARCOR1ALDH1A1LMNAKMT2A | |
| SCHEMBL7761464 | 0.83 | KMT2A (0.60) | KDM1ARCOR1MAPK1ALDH1A1LMNA | |
| SCHEMBL22338581 | 0.82 | KDM1A (0.57) | KDM1ARCOR1MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | SCHARPE SIMON LODEWIJK (BE) | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | FAP, CTSC, DPP4 | KDM1A 1959/4885RCOR1 3365/4885MAPK1 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.