Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315510 | 0.90 | KDM1A (0.67) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL7624965 | 0.89 | KDM1A (0.67) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL7687546 | 0.88 | LMNA (0.57) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL7758133 | 0.87 | KDM1A (0.59) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL11925397 | 0.86 | KDM1A (0.64) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL7761464 | 0.86 | KMT2A (0.60) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL3694153 | 0.86 | POLB (0.68) | KDM1ARCOR1RAB9AKMT2AGAA | |
| SCHEMBL10542510 | 0.84 | KMT2A (0.55) | KDM1ARCOR1KMT2AGAALMNA | |
| SCHEMBL9635671 | 0.84 | POLB (0.74) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL7622075 | 0.83 | KDM1A (0.60) | KDM1ARCOR1RAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062242-A1 | PRODRUGS OF SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2001-08-30 | — | — | WO | disclosed |
| EP-0730591-B1 | ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES | UPJOHN CO (US) | 1999-07-14 | — | — | EP | disclosed |
| US-5652238-A | WATER SOLUBILITY; ANTIMICROBIAL AGENTS EFFECTIVE AGAINST RESISTANT STAPHYLOCOCCI, ENTEROCOCCI, AND STREPTOCOCCI | PHARMACIA & UPJOHN COMPANY (US) | 1997-07-29 | — | — | US | disclosed |
| EP-0730591-A1 | ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014684-A1 | ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES | THE UPJOHN COMPANY (US) | 1995-06-01 | — | — | WO | disclosed |