SCHEMBL22339066

SCHEMBL22339066

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCCc1ccccc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.51
▸ NPY5R Q15761 10/20 0.51
▸ NPY1R P25929 9/20 0.51
▸ NPY2R P49146 7/20 0.51
▸ MC4R P32245 4/20 0.49
▸ CALCRL Q16602 1/20 0.43
▸ FCER2 P06734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22485383 1.00 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RMC4R
SCHEMBL22339062 0.94 NPY4R (0.55) NPY4RNPY5RNPY1RNPY2RMC4R
SCHEMBL20046064 0.89 MC4R (0.48) NPY4RNPY5RNPY1RNPY2RMC4R
SCHEMBL20045521 0.89 MC4R (0.48) NPY4RNPY5RNPY1RNPY2RMC4R
SCHEMBL24114780 0.87 NPY4R (0.49) NPY4RNPY5RNPY1RNPY2R
SCHEMBL24919552 0.87 NPY4R (0.57) NPY4RNPY5RNPY1RNPY2RCALCRL
SCHEMBL14811912 0.86 MC4R (0.57) MC4R
SCHEMBL22339064 0.84 MC4R (0.55) MC4R
SCHEMBL29697024 0.84 KISS1R (0.45) NPY4RNPY5RNPY1RNPY2RMC4R
SCHEMBL30548763 0.84 NPY4R (0.55) NPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3704134-B1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS BV (NL) 2021-12-22 — — EP disclosed
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS B.V. (NL) 2020-10-01 — — US disclosed
WO-2020161255-A1 NOVEL METHOD FOR REDUCING HAIR GROWTH DSM IP ASSETS B.V. (NL) 2020-08-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES VIP, CLPP, SGTA NPY4R 2803/4885NPY5R 3428/4885NPY1R 3111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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