Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22558332 | 1.00 | CA2 (0.54) | CA2CA1CA9ALDH1A1CYP2A6 | |
| SCHEMBL8411274 | 0.87 | CA1 (0.54) | CA2CA1CA9HTTLMNA | |
| SCHEMBL1196442 | 0.86 | MEN1 (0.60) | CA2ALDH1A1KMT2AMEN1CA12 | |
| SCHEMBL4126086 | 0.86 | MEN1 (0.60) | CA2CA1CA9ALDH1A1KMT2A | |
| SCHEMBL9852204 | 0.86 | MEN1 (0.60) | CA2CA1CA9ALDH1A1KMT2A | |
| SCHEMBL18179825 | 0.86 | MEN1 (0.60) | CA2CA1CA9ALDH1A1KMT2A | |
| SCHEMBL8926657 | 0.85 | MEN1 (0.50) | CA2CA1CA9ALDH1A1KMT2A | |
| SCHEMBL11569651 | 0.84 | GAA (0.58) | CA2CA1CA9ALDH1A1KMT2A | |
| Iodide SCHEMBL22068772 | 0.84 | CA2 (0.59) | CA2CA1CA9ALDH1A1KMT2A | |
| SCHEMBL8058025 | 0.83 | ENPP2 (0.49) | CA2CA1CA9ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949655-B1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEM IND CO (JP) | 2019-05-15 | — | — | EP | disclosed |
| US-9895454-B2 | Metal oxide catalyzed radiofluorination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-9895454-B2 | Metal oxide catalyzed radiofluorination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-9895454-B2 | Metal oxide catalyzed radiofluorination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
| US-9707551-B2 | Reaction catalyst for cross-coupling and method for manufacturing aromatic compound | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| EP-1581467-B1 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-10-12 | — | — | EP | disclosed |
| EP-2583958-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-08-10 | — | — | EP | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
| US-6235938-B1 | ARYLATION IN THE PRESENCE OF A BASE AND TRANSITION METAL CATALYSTS TO FORM N-ARYLAMINE AND GROUP 8 METAL | YALE UNIVERSITY | 2001-05-22 | — | — | US | disclosed |
| EP-0519299-B1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1999-08-11 | — | — | EP | disclosed |
| EP-0519298-B1 | Radiation-sensitive sulfonic acid esters and their use | HOECHST AG (DE) | 1995-09-13 | — | — | EP | disclosed |
| US-5442061-A | Recording, photoresists, printing plates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |
| US-5364734-A | Sulfonated triazines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5298364-A | Negative photoresists, acid crosslinking | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | disclosed |
| EP-0519298-A1 | Radiation-sensitive sulfonic acid esters and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | EP | disclosed |
| EP-0519299-A1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | EP | disclosed |
| US-5166403-A | Liquid crystals | SHOWA DENKO K.K. (JP) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224851-A1 | METAL OXIDE CATALYZED RADIOFLUORINATION | TRHDE, TPO, TERT | CA2 95/4885CA1 29/4885CA9 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.