SCHEMBL2234044

SCHEMBL2234044

CCN(CC)c1ccccc1C1SCCCS1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.32
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TAAR1 Q96RJ0 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1757653 0.81 MAPT (0.33) FAAHMEN1MAPTKMT2ANPSR1
SCHEMBL5909047 0.75 FAAH (0.38) FAAHMEN1MAPTKMT2ANPSR1
SCHEMBL11792582 0.73 FAAH (0.40) FAAHMEN1MAPTKMT2ANPSR1
SCHEMBL26108908 0.71 MEN1 (0.42) FAAHMEN1MAPTKMT2ANPSR1
SCHEMBL9778748 0.70 HTR2A (0.48) MEN1MAPTKMT2ANPSR1
SCHEMBL2234042 0.69 ALDH1A1 (0.42) MEN1MAPTKMT2ANPSR1TSHR
SCHEMBL6299189 0.69 TSHR (0.46) MEN1MAPTKMT2ATSHR
SCHEMBL31718395 0.69 TSHR (0.46) MEN1MAPTKMT2ATSHR
SCHEMBL16597319 0.67 MEN1 (0.54) FAAHMEN1MAPTKMT2ANPSR1
SCHEMBL2279716 0.67 KDM1A (0.44) FAAHMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981990-B2 Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORPORATION (JP) 2011-07-19 US claimed
JP-2010538109-A 2010-12-09 JP claimed
EP-2193150-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER Bridgestone Corporation (JP) 2010-06-09 EP claimed
WO-2009032154-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-12 WO claimed
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-05 US claimed
EP-2193150-B1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORP (JP) 2020-09-23 EP disclosed
US-7981990-B2 Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORPORATION (JP) 2011-07-19 US disclosed
EP-2193150-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER Bridgestone Corporation (JP) 2010-06-09 EP disclosed
WO-2009032154-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-12 WO disclosed
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER FGB, FIP1L1, PUF60 FAAH 92/4885MEN1 1390/4885MAPT 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.