SCHEMBL2234042

SCHEMBL2234042

CCN(CC)c1ccc(C2SCCCS2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
TSHR P16473 3/20 0.42
GFER P55789 2/20 0.42
PSMD14 O00487 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH3A1 P30838 1/20 0.40
ALDH1A3 P47895 1/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.38
MITF O75030 1/20 0.38
MAPT P10636 1/20 0.38
POLB P06746 3/20 0.38
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12590630 0.83 KMT2A (0.44) ALDH1A1TSHRGFERKMT2AMEN1
SCHEMBL1757650 0.79 ALDH1A1 (0.51) ALDH1A1TSHRCYP3A4MAPK1RECQL
SCHEMBL7632848 0.78 TSHR (0.44) ALDH1A1TSHRMAPK1TDP1L3MBTL1
SCHEMBL10975031 0.76 ALDH1A1 (0.41) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL9271980 0.72 MAPT (0.47) ALDH1A1TSHRTDP1KMT2AKDM4E
SCHEMBL5146739 0.72 ALDH1A1 (0.48) ALDH1A1TSHRGFERPSMD14CYP3A4
SCHEMBL5146741 0.72 RAB9A (0.50) ALDH1A1TSHRGFERPSMD14CYP3A4
SCHEMBL9778743 0.71 MAOA (0.53) ALDH1A1TSHRTDP1L3MBTL1KMT2A
SCHEMBL5146728 0.71 ALDH1A1 (0.50) ALDH1A1TSHRGFERPSMD14CYP3A4
SCHEMBL1735497 0.71 ALDH1A1 (0.74) ALDH1A1TSHRGFERPSMD14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981990-B2 Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORPORATION (JP) 2011-07-19 US claimed
JP-2010538109-A 2010-12-09 JP claimed
EP-2193150-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER Bridgestone Corporation (JP) 2010-06-09 EP claimed
WO-2009032154-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-12 WO claimed
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-05 US claimed
EP-2193150-B1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORP (JP) 2020-09-23 EP disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-7981990-B2 Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORPORATION (JP) 2011-07-19 US disclosed
EP-2193150-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER Bridgestone Corporation (JP) 2010-06-09 EP disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
WO-2009032154-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-12 WO disclosed
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER FGB, FIP1L1, PUF60 ALDH1A1 1640/4885TSHR 4453/4885GFER 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.