SCHEMBL1757653

SCHEMBL1757653

CN(C)c1ccccc1C1SCCCS1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.33
ALDH1A1 P00352 3/20 0.33
GAA P10253 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FAAH O00519 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CHEK1 O14757 1/20 0.32
NEK2 P51955 1/20 0.32
LIMK1 P53667 1/20 0.32
DYRK1A Q13627 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GPR3 P46089 1/20 0.31
GSK3B P49841 1/20 0.30
HTR6 P50406 1/20 0.30
GLI1 P08151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2234044 0.81 FAAH (0.32) MAPTTSHRFAAHMEN1KMT2A
SCHEMBL11792582 0.80 FAAH (0.40) MAPTALDH1A1GAATP53TSHR
SCHEMBL5909047 0.80 FAAH (0.38) MAPTALDH1A1TSHRFAAHMEN1
SCHEMBL26108908 0.75 MEN1 (0.42) MAPTTSHRFAAHMEN1KMT2A
SCHEMBL11685520 0.73 KDM4E (0.37) MAPTALDH1A1GAATP53TSHR
SCHEMBL16597319 0.71 MEN1 (0.54) MAPTALDH1A1GAATSHRSMN1; SMN2
SCHEMBL29760847 0.71 KDM1A (0.44) GAAFAAHMEN1KMT2ANPSR1
SCHEMBL2279716 0.71 KDM1A (0.44) GAAFAAHMEN1KMT2ANPSR1
SCHEMBL9778659 0.70 L3MBTL1 (0.47) TSHRMEN1KMT2AHTR2AL3MBTL1
SCHEMBL30669509 0.70 L3MBTL1 (0.47) TSHRMEN1KMT2AHTR2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981990-B2 Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORPORATION (JP) 2011-07-19 US claimed
JP-2010538109-A 2010-12-09 JP claimed
EP-2193150-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER Bridgestone Corporation (JP) 2010-06-09 EP claimed
WO-2009032154-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-12 WO claimed
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-05 US claimed
EP-2193150-B1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORP (JP) 2020-09-23 EP disclosed
EP-2266993-B1 The use of sulfur containing initiators for anionic polymerization of monomers BRIDGESTONE CORP (JP) 2017-06-14 EP disclosed
EP-2658898-B1 COUPLED POLYMERS AND METHODS FOR MAKING SAME BRIDGESTONE CORP (JP) 2016-10-12 EP disclosed
US-9441097-B2 Rubber composition and tire produced by using the same BRIDGESTONE CORPORATION (JP) 2016-09-13 US disclosed
EP-2657282-B1 RUBBER COMPOSITION AND TIRE PRODUCED BY USING THE SAME BRIDGESTONE CORP (JP) 2016-08-24 EP disclosed
US-9221923-B2 Coupled polymers and methods for making same BRIDGESTONE CORPORATION (JP) 2015-12-29 US disclosed
EP-1565476-B1 THE USE OF SULFUR CONTAINING INITIATORS FOR ANIONIC POLYMERIZATION OF MONOMERS BRIDGESTONE CORP (JP) 2015-03-25 EP disclosed
US-20080004385-A1 Sulfur containing initiators for anionic polymerization of monomers BRIDGESTONE CORPORATION 2008-01-03 US disclosed
EP-1805223-A1 FUNCTIONALIZED POLYMER WITH LINKING GROUP Bridgestone Corporation (JP) 2007-07-11 EP disclosed
US-20070083023-A1 Use of sulfur containing initiators for anionic polymerization of monomers BRIDGESTONE CORPORATION 2007-04-12 US disclosed
US-7153919-B2 Use of sulfur containing initiators for anionic polymerization of monomers BRIDGESTONE CORPORATION (JP) 2006-12-26 US disclosed
WO-2006047328-A1 FUNCTIONALIZED POLYMER WITH LINKING GROUP BRIDGESTONE CORPORATION (JP) 2006-05-04 WO disclosed
US-20060030657-A1 Use of sulfur containing initiators for anionic polymerization of monomers BRIDGESTONE CORPORATION (JP) 2006-02-09 US disclosed
EP-1565476-A2 THE USE OF SULFUR CONTAINING INITIATORS FOR ANIONIC POLYMERIZATION OF MONOMERS Bridgestone Corporation (JP) 2005-08-24 EP disclosed
WO-2004041870-A2 THE USE OF SULFUR CONTAINING INITIATORS FOR ANIONIC POLYMERIZATION OF MONOMERS BRIDGESTONE CORPORATION (JP) 2004-05-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER FGB, FIP1L1, PUF60 MAPT 2672/4885ALDH1A1 1640/4885GAA 2367/4885
US-20060030657-A1 Use of sulfur containing initiators for anionic polymerization of monomers TST, ESD, VCL MAPT 2123/4885ALDH1A1 3070/4885GAA 2410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.