Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL22345233 | 0.97 | NAAA (0.56) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL27900198 | 0.90 | NAAA (0.62) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL17219584 | 0.90 | NAAA (0.62) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL27325180 | 0.89 | NAAA (0.60) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL17219527 | 0.88 | NAAA (0.59) | NAAARAD52NPSR1FAAHDGKA | |
| Propionic Acid SCHEMBL22345230 | 0.87 | NAAA (0.59) | NAAARAD52NPSR1FAAHDGKA | |
| Propionic Acid SCHEMBL27981082 | 0.86 | NAAA (0.58) | NAAARAD52NPSR1FAAHDGKA | |
| Propionic Acid SCHEMBL22345225 | 0.86 | NAAA (0.58) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL16153182 | 0.83 | ATM (0.52) | NAAARAD52NPSR1FAAHDGKA | |
| Propionic Acid SCHEMBL7647609 | 0.80 | NAAA (0.81) | NAAARAD52NPSR1FAAHDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165069-A1 | NON-CHLORINATED OPEN PLANT CLEANING COMPOSITION | BASF SE (DE) | 2020-08-20 | — | — | WO | disclosed |