Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP12 | P39900 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677294 | 0.89 | CA12 (0.40) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL21540832 | 0.80 | CA12 (0.42) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL15592453 | 0.79 | CA12 (0.47) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL7840740 | 0.74 | CA12 (0.52) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL19402797 | 0.73 | CA12 (0.50) | CA12CA14CA2KDM4EALDH1A1 | |
| SCHEMBL8930152 | 0.72 | CA12 (0.48) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL2583703 | 0.72 | CA12 (0.48) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL22345238 | 0.71 | TSHR (0.41) | CA12CA14CA2GAATET2 | |
| SCHEMBL22475391 | 0.70 | CA12 (0.47) | CA12CA14CA2GAAKDM4E | |
| SCHEMBL4674334 | 0.70 | CA12 (0.47) | CA12CA14CA2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220142164-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-20220112175-A1 | PYRIDAZINES HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-14 | — | — | US | disclosed |
| US-20220104492-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-07 | — | — | US | disclosed |
| EP-3927697-A1 | PYRIDAZINES HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-12-29 | — | — | EP | disclosed |
| EP-3923728-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3924347-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| CN-113439081-A | Pyridazinium compounds for use in methods of controlling unwanted plant growth | 先正达农作物保护股份公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-113423274-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113423704-A | Pyridazine herbicidal compounds | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2020164973-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020165321-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020165310-A1 | PYRIDINIUM COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220142164-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | CA12 2083/4885CA14 1962/4885CA2 257/4885 |
| US-20220112175-A1 | PYRIDAZINES HERBICIDAL COMPOUNDS | DDT, PLPBP, CYP4Z1 | CA12 4110/4885CA14 4344/4885CA2 1182/4885 |
| US-20220104492-A1 | PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH | DDT, PNPO, PLPBP | CA12 4665/4885CA14 4574/4885CA2 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.