SCHEMBL22345263

SCHEMBL22345263

CC(C)(C)COS(=O)(=O)CCN

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.33
LMNA P02545 1/20 0.33
SLC6A6 P31641 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11979484 0.81 CYP2C19 (0.33) CYP2C19
SCHEMBL11051802 0.78 LMNA (0.32) CYP2C19LMNASLC6A6BLM
SCHEMBL31656227 0.77 CA1 (0.54) CYP2C19LMNASLC6A6BLM
SCHEMBL20743841 0.77
SCHEMBL29095929 0.75 CYP2C19 (0.36) CYP2C19
SCHEMBL5170438 0.75 TP53 (0.33)
Hydrochloric Acid SCHEMBL20743682 0.75
SCHEMBL23881716 0.74
SCHEMBL724787 0.74
SCHEMBL23881700 0.74 ATR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220142164-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-05-12 US disclosed
US-20220142164-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-05-12 US disclosed
US-20220112175-A1 PYRIDAZINES HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-04-14 US disclosed
EP-3927697-A1 PYRIDAZINES HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2021-12-29 EP disclosed
EP-3923728-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2021-12-22 EP disclosed
CN-113423274-A Herbicidal compounds 先正达农作物保护股份公司 2021-09-21 CN disclosed
CN-113423704-A Pyridazine herbicidal compounds 先正达农作物保护股份公司 2021-09-21 CN disclosed
WO-2020165321-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed
WO-2020165310-A1 PYRIDINIUM COMPOUNDS AND THEIR USE AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142164-A1 HERBICIDAL COMPOUNDS DDT, ACHE, GSTO1 CYP2C19 242/4885LMNA 3760/4885SLC6A6 2070/4885
US-20220112175-A1 PYRIDAZINES HERBICIDAL COMPOUNDS DDT, PLPBP, CYP4Z1 CYP2C19 211/4885LMNA 3593/4885SLC6A6 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.