SCHEMBL22345335

SCHEMBL22345335

CCC(C[PH](=O)O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC8 Q9BY41 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ ESR1 P03372 3/20 0.38
▸ ESR2 Q92731 2/20 0.38
▸ ADRA2A P08913 1/20 0.37
▸ ADRA2B P18089 1/20 0.37
▸ ADRA2C P18825 1/20 0.37
▸ ACHE P22303 1/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ CYP1A2 P05177 2/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ CYP2D6 P10635 2/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ STAT3 P40763 1/20 0.33
▸ GRIA4 P48058 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350645 0.84 GABBR2 (0.38) LMNASMN1; SMN2ACHEMEN1KMT2A
SCHEMBL2510168 0.83 LMNA (0.45) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL28502445 0.83 HRH3 (0.38) ALDH1A1LMNASMN1; SMN2ESR1ESR2
SCHEMBL3989199 0.77 ADRA2A (0.48) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL16979038 0.74 ESR1 (0.44) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL29110964 0.72 STAT3 (0.45) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL11322774 0.72 FFAR1 (0.54) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL185573 0.70 CYP2C19 (0.50) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL9397889 0.70 ALDH1A1 (0.44) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2
SCHEMBL19803213 0.70 ADRA2A (0.42) HDAC8HDAC6ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122364-A1 FLAME RETARDANT MIXTURES, FLAME-RETARDANT POLYMER COMPOSITIONS, CABLES ENDOWED THEREWITH AND USE THEREOF CLARIANT INTERNATIONAL LTD (CH) 2025-04-17 — — US disclosed
US-20250122426-A1 FLAME-RETARDANT MIXTURES, FLAME-RETARDING POLYMER COMPOSITIONS, CABLE EQUIPPED THEREWITH AND USE THEREOF CLARIANT INTERNATIONAL LTD (CH) 2025-04-17 — — US disclosed
US-20220135773-A1 FLAME RETARDANT MIXTURES, FLAME-RETARDANT POLYMER COMPOSITIONS, CABLES ENDOWED THEREWITH AND USE THEREOF CLARIANT INTERNATIONAL LTD (CH) 2022-05-05 — — US disclosed
US-20220025268-A1 FLAME-RETARDANT MIXTURES, FLAME-RETARDING POLYMER COMPOSITIONS, CABLE EQUIPPED THEREWITH AND USE THEREOF CLARIANT INTERNATIONAL LTD (CH) 2022-01-27 — — US disclosed
EP-3924414-A1 FLAME RETARDANT MIXTURES, FLAME-RETARDANT POLYMER COMPOSITIONS, CABLES ENDOWED THEREWITH AND USE THEREOF Clariant International Ltd (CH) 2021-12-22 — — EP disclosed
CN-113454154-A Flame-retardant mixture, flame-retardant polymer composition, cable provided with same and use thereof 科莱恩国际有限公司 2021-09-28 — — CN disclosed
CN-113383055-A Flame retardant mixture, flame retardant polymer composition, cable provided with the same and use thereof 科莱恩国际有限公司 2021-09-10 — — CN disclosed
CN-107828207-B Flame retardant-stabilizer combinations for thermoplastic polymers 科莱恩塑料和涂料有限公司 2020-12-25 — — CN disclosed
WO-2020165018-A1 FLAME RETARDANT MIXTURES, FLAME-RETARDANT POLYMER COMPOSITIONS, CABLES ENDOWED THEREWITH AND USE THEREOF CLARIANT PLASTICS & COATINGS LTD (CH) 2020-08-20 — — WO disclosed
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