Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 10/20 | 0.44 |
| ▸ | S100A10 | P60903 | 10/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MYLK | Q15746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295548 | 0.86 | ANXA2 (0.55) | ANXA2S100A10CCR1ALDH1A1L3MBTL1 | |
| SCHEMBL2234316 | 0.78 | ANXA2 (0.53) | ANXA2S100A10ALDH1A1NPC1RAB9A | |
| SCHEMBL2232974 | 0.70 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL2234993 | 0.70 | ANXA2 (0.65) | ANXA2S100A10CCR1CCR2ALDH1A1 | |
| SCHEMBL2231482 | 0.69 | ANXA2 (0.58) | ANXA2S100A10CCR1CCR2ALDH1A1 | |
| SCHEMBL2230926 | 0.69 | ANXA2 (0.66) | ANXA2S100A10CCR1CCR2ALDH1A1 | |
| SCHEMBL2233246 | 0.67 | CCR1 (0.59) | ANXA2S100A10CCR1ALDH1A1USP2 | |
| SCHEMBL6720978 | 0.67 | CCR1 (0.54) | CCR1CCR2ALDH1A1L3MBTL1 | |
| SCHEMBL2234747 | 0.67 | L3MBTL1 (0.39) | ANXA2S100A10CCR1CCR2ALDH1A1 | |
| SCHEMBL2236163 | 0.67 | ANXA2 (0.66) | ANXA2S100A10CCR1CCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |