SCHEMBL2234747 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	L3MBTL1	Q9Y468	3/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	CCR1	P32246	2/20	0.38

▸	CCR2	P41597	1/20	0.38

▸	ANXA2	P07355	9/20	0.38

▸	S100A10	P60903	9/20	0.38

▸	MGLL	Q99685	1/20	0.38

▸	CES2	O00748	1/20	0.38

▸	CES1	P23141	1/20	0.38

▸	POLB	P06746	1/20	0.34

▸	ALDH1A1	P00352	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2295543	0.86	ANXA2 (0.48)	L3MBTL1ANXA2S100A10MGLLALDH1A1
SCHEMBL2234313	0.78	ANXA2 (0.45)	NPC1RAB9AANXA2S100A10MGLL
SCHEMBL2234748	0.67	ANXA2 (0.44)	L3MBTL1NPC1RAB9ACCR1CCR2
SCHEMBL15139601	0.65	CCR1 (0.52)	L3MBTL1CCR1CCR2MGLLCES2
SCHEMBL2230926	0.60	ANXA2 (0.66)	CCR1CCR2ANXA2S100A10ALDH1A1
SCHEMBL2156105	0.59	CES2 (1.00)	L3MBTL1NPC1RAB9ACES2CES1
SCHEMBL14135917	0.59	ALDH1A1 (0.76)	L3MBTL1NPC1RAB9ACES2CES1
SCHEMBL195263	0.59	ALDH1A1 (0.76)	L3MBTL1NPC1RAB9ACES2CES1
SCHEMBL6224695	0.57	RAB9A (1.00)	L3MBTL1NPC1RAB9ACES2CES1
SCHEMBL6199337	0.57	RAB9A (1.00)	L3MBTL1NPC1RAB9ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011092505-A1	S100 PROTEIN BINDING INTERACTION INHIBITORS	CANCER RESEARCH TECHNOLOGY LIMITED (GB)	2011-08-04	—	—	WO	disclosed