Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 11/20 | 0.55 |
| ▸ | S100A10 | P60903 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234748 | 0.86 | ANXA2 (0.44) | ANXA2S100A10ALDH1A1L3MBTL1CCR1 | |
| SCHEMBL2234316 | 0.73 | ANXA2 (0.53) | ANXA2S100A10ALDH1A1CNR2TP53 | |
| SCHEMBL2236163 | 0.71 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1MEN1ALOX15 | |
| SCHEMBL27449104 | 0.69 | ALDH1A1 (0.64) | ALDH1A1CNR2KMT2AGAAL3MBTL1 | |
| SCHEMBL2231482 | 0.67 | ANXA2 (0.58) | ANXA2S100A10ALDH1A1MEN1ALOX15 | |
| SCHEMBL2232974 | 0.65 | ANXA2 (0.65) | ANXA2S100A10ALDH1A1 | |
| SCHEMBL14098923 | 0.64 | KMT2A (0.61) | ALDH1A1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL2232333 | 0.64 | ANXA2 (0.66) | ANXA2S100A10ALDH1A1MEN1ALOX15 | |
| SCHEMBL2236328 | 0.64 | ALDH1A1 (0.66) | ANXA2S100A10ALDH1A1MEN1ALOX15 | |
| SCHEMBL9861628 | 0.63 | PLK1 (0.64) | ALDH1A1CNR2KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |